Let’s take a look at syphilis causes, symptoms, incubation periods, infectious paths and inspections and treatments. Syphilis is a prostitution infectious disease caused by Treponema Pallidum, which can cause serious complications without proper treatment. Syphilis is performed in 1, 2, and incubation period, depending on the time after infection, and characteristic symptoms appear in each stage. In particular, syphilis has a variety of symptoms, called ‘great imitators’, and can last from several years to decades without symptoms during the incubation period. If you find it early and treat it with penicillin, you can cure it, but if you leave it without treatment, you can cause serious complications.
Syphosis symptoms/incubation period
Syphilis is a prostitute caused by Treponema Pallidum. System is divided into 1, 2, and incubation period, depending on the time after infection, and characteristic symptoms appear in each stage. In particular, incubation can last from several years to decades without external symptoms, also called the ‘great imitation’. If you do not receive proper treatment, it can cause serious complications, so early diagnosis and treatment are important.
Syphranic symptoms of syphilis
Syphragm is divided into four stages depending on the time and symptoms of infection:
- 1st syphilis: Appears between 10 and 90 days (average 2-6 weeks) after infection. The main symptoms are painless ulcers in the infection. This ulcer is usually hard, round, and no pain. The size is about 0.3 ~ 3.0cm, and it disappears naturally after 3 to 6 weeks without treatment. For women, mainly in cervicals (44%), heterosexual men are mainly in penis (99%), male homosexuals occur in anus and rectum (34%). At this time, the infection is very strong.
- 2nd syphilis: After 4 to 8 weeks after the first ulcer was healed (7-10 weeks after infection). The main symptoms are characteristic of the rashes that appear on the palms and soles of the feet. In addition, fever, fatigue, loss of appetite, weight loss, headaches, hair loss, and lymph node edema may occur. In about 50% of the patient, the hypertrophy is observed, and about 10% affect other organs. This time also has high infection.
Syphilis
Lady syphilis begins after the symptoms of 1 and 2 disappear:
- Early latent syphilis: A year after infection, there is no external symptoms, but it has a positive reaction in serematic tests. At this time, there is still a high infection, and in about 25%of the patient, syphilis bacteria remain active, resulting in the symptoms of the second syphilis.
- Late latent syphilis: After more than one year after infection, the infection is lower than that of the initial latent syphilis. Without symptoms, it can last from several years to decades (up to 30-35 years). If you do not treat, you can proceed with a 3rd syphilis in 15-40%of patients.
Complications with the 3rd syphilis
Untreated syphilis can cause serious complications:
- Nerve syphilis: It occurs in about 5%of untreated syphilis patients. Symptoms such as headaches, neck stiffness, decrease in concentration, memory loss, insomnia, etc. can cause stroke in severe cases.
- Cardiovascular syphilis: It affects the heart and the vascular vessels, which can cause coronary artery stenosis.
- Rubber: A variety of organs, such as skin, bones, and liver, may cause non -cancer tumors, and the symptoms vary depending on the subdivided areas.
Syphilis is found early and can be cured by proper antibiotic treatment. However, if left untreated, it can cause serious complications, so it is important to have regular checkups after dangerous sex. In particular, diagnosis through blood tests is essential because there is no symptom in the incubation period.
Syphosis cause/transmission
Syphilis is mainly spread through sexual contact, and it can cause serious complications without proper treatment. Syphilis is performed in 1, 2, and incubation period, depending on the time after infection, and characteristic symptoms appear in each stage. In particular, syphilis has a strong contagious power, which can be infected with a probability of about 30-60%with one sexual contact with patients with early stage.
Syphilis
Treponema Palidium, the cause of syphilis, has the following features:
- Spirochete: Treponema Palidium is a spiral -shaped bacterium belonging to the Spiro Heta. This bacterium has a very short survival time outside the human body, making it difficult to spread by everyday contact. But in the human body, it can survive for a long time and affect several organs.
- Infection: Syphilis has a very strong infection, and even if it is exposed to only 57 bacteria, the probability of infection is 50%. This means that infections can occur easily even with a relatively small number of bacteria compared to other prostitution.
- Incubation: Treponema Palidium has the ability to lurk for a long time in the body, which may remain in the body for years to decades without treatment. Because of these characteristics, syphilis is also called ‘great imitation’.
Syphilis
System can be spread through various paths, and the main infection paths are as follows:
- Sexual contact: The most common path of infection, it is spread through vaginal intercourse, anal sex, oral intercourse. In particular, direct contact with syphilis lesions (ulcer) is the main radio wave. Sexual contact with syphilis can be infected with a chance of about 30-60%, and the use of condoms can reduce the risk of infection.
- Vertical infection: If a pregnant woman is infected with syphilis, she can spread to her fetus. This is called congenital syphilis and can be spread during pregnancy or childbirth. Depending on the pregnant woman’s syphilis infection period, the fetus may be stillborn or serious health problems after birth.
Syphorian infection
There are several factors that increase the risk of syphilis infection:
- Unprotected sex: Sexual intercourse that does not use condoms is the main risk factor of syphilis infection. In particular, sex with various partners and sex with unspecified majority increase the risk of infection. Direct contact with people with syphilis lesions increases the probability of infection, so safe sexual practice is important.
- Other prostitutes: If you already have other prostitutes (STI), there is a higher risk of syphilis. Other sexual infectious diseases such as HIV often increase with syphilis. This is because the weakening of the immune system and the mucosal damage make it more vulnerable to infection.
Prevention of syphilis
There are effective ways to prevent syphilis infections:
- Safe sexRight use of condoms is effective in preventing sexual infectious diseases, including syphilis. It is important to use condoms in every sexual intercourse, and to use the appropriate protection during oral intercourse. Limiting the number of sexual partners is also a way to reduce the risk of infection.
- Regular examination: It is important for sexually active people to have a syphilis test regularly. In particular, it is recommended that high -risk groups (men, etc. have sex with men) are inspected every three to six months. Early detection and treatment can prevent syphilis complications and prevent them from spreading to others.
Syphilis is found early and can be cured by proper antibiotic treatment. However, if left untreated, it can cause serious complications, so it is important to have regular checkups after dangerous sex. To prevent syphilis, safe sexual intercourse and regular health checkups are essential.
Syphilic test/treatment
Syphilic tests are largely divided into nonspecific antibody tests and specific antibody tests. Treatment is mainly used with penicillin antibiotics. In particular, the test method and treatment method may vary depending on the stage of syphilis and the period of infection, so the exact diagnosis of a specialist is important.
Types of syphilis tests
Syphilic tests are largely divided into two types:
- Nonspecific antibody test: VEDRL (VENERAL DISEASE Research Laboratory) and Rapid Plasma Reagin (RPR) are typical. These tests do not directly detect antibodies for syphilis bacteria, but measure the body reactions by syphilis infection. For 3 to 6 weeks after infection, the results can be negative, so there is a possibility of gastric. In addition, false tests may occur in pregnancy, viral infections, HIV infections, and autoimmune diseases, which may require additional tests. This test is useful for monitoring the therapeutic effect and evaluates the therapeutic response through changes in titer after treatment.
- Peculiar: FTA-ABS (Fluorescent Treponemal Antibody Absorption), TPHA (T. Pallidum Hemagglutination Test), TP-EIA (T. Pallidum Enzyme IMMUNOASSAY), TP-Clia (T. Pallidum ChemilumineScent ImmunoAssay). These tests have a high specificity by detecting antibodies that are specific for syphilis bacteria. However, most of them remain positive after treatment, and are useful for checking the past infection rather than judging the current infection. Therefore, the current infection should be evaluated with the nonspecific antibody test.
Step -by -step treatment of syphilis
Syphragom treatment is applied differently depending on the infection stage:
- 1st and 2nd syphilis: Penicillin G -benzine is a standard treatment to inject 2.4 million units once. This treatment is effective for most early syphilis patients and is sufficient for one injection. Injections are usually administered in both hip muscles each 1.2 million units each. For patients with penicillin allergies, you can use Doxycycline or ceftriaxone as an alternative drug.
- Lurking syphilis: Early incubation syphilis (within 1 year after infection) is treated with penicillin G benzatin 2.4 million units in the same as the first and second syphilis. In the case of late incubation syphilis (or unknown for more than one year after infection), the penicillin G benzatin 2.4 million units are administered three times every 7 to 10 days. This is to administer a total of 7.2 million penicillin, to effectively remove the lurking syphilis bacteria for a long time.
Tracement management after treatment
Proper tracking management after syphilis is important:
- Serum: Regular RPR or VDRL test is performed to evaluate the therapeutic effect. If the treatment is successful, the titer will gradually decrease. In the case of the first syphilis, the titer decreases four times after 6 months, decreases 8 times after 12 months, and decreases 16 times after 24 months. The second syphilis is expected to decrease 16 times after 6 months and 12 months after 12 months. The 3rd syphilis is based on four times decrease in 12 months.
- Treatment failure evaluation: After treatment, if you do not decrease more than four times after treatment, or more than four times after 6 months, or if the symptoms persist, it is considered a failure and considering the furniture. In this case, checking through the spinal cage may be required to check whether it is neurological.
Latest treatment alternative
In addition to penicillin, various antibiotics options are being studied:
- Dalbavancin: Lipoglycopeptide -based antibiotics, which have a long -time act, allowing a single capacity therapy. This has the advantage of greatly improving medication compliance. It is attracting attention as a promising alternative because it can maintain the level of treatment for up to 6 weeks in human plasma.
- CEFIXIMEOral antibiotics can be an alternative in an environment where patients with penicillin allergies or in injections are difficult. However, evidence of the effect other than the initial stage syphilis is limited.
Syphilis is a very important disease in early detection and proper treatment. Most of them can be cured through accurate tests and appropriate antibiotics, but regular tracking tests are required after treatment. In particular, it is important for prevention of re -infection to be tested and treated with sex partners.
FAQ
Q: What is the main symptom of syphilis?
A: syphilis shows different symptoms step by step. The first syphilis has a painless ulcer on the infectious area, and the second syphilis has rashes, fever, fatigue, and headaches on the palms and soles of the palms. There is no symptom in the incubation period, and the third syphilis can seriously damage various organs, such as cardiovascular and nervous system.
Q: How much is the incubation of syphilis?
A: syphilis incubation is divided into early and later. Early incubation syphilis is a period of less than a year after infection, but there is no symptoms, but is positive in serum -based tests and is still infected. Later latent syphilis has been more than a year after infection, and it can last from several years to decades without treatment.
Q: How is syphilis spread?
A: syphilis is mainly spread through sexual contact. Direct contact with syphilis lesions (ulcer) is the main radio wave method and can be infected with a probability of about 30-60%when sexual contact with syphilis patients. Also, if a pregnant woman is infected with syphilis, it may be spread to the fetus, which is called congenital syphilis.
Q: How is syphilis test?
A: syphilis tests are largely divided into nonspecific antibody tests (VDRL, RPR) and specific antibody tests (FTA-ABS, TPHA). Non -specific antibody tests measure the body reactions by syphilis infection and are useful for monitoring the therapeutic effect. Unusual antibody tests are used to directly detect antibodies that are specific for syphilis bacteria, and are used to identify past infections.
Q: How is syphilis treatment done?
A: syphilis treatment mainly uses penicillin G benzatin injections. 1, 2, and initial latent syphilis are muscle injecting 2.4 million units once, and late latent syphilis administers 2.4 million units three times every 7 to 10 days. Patients with penicillin allergies can use poison cyclin or cestree evil as an alternative drug.
Q: How do I follow tracking after syphilis treatment?
A: After treatment, the therapeutic effect is evaluated through regular serum -tracking tests (RPR or VDRL). If the treatment is successful, the titer will gradually decrease. If the titer is more than four times after treatment, it does not decrease more than four times after six months, or if the symptoms persist, it is necessary to consider the furniture treatment.
-- CONTENT END 2 -->